How Often Should I Take PrEP?
Daily PrEP (1 pill per day) Routine
Depending on what body parts you use during sex, daily PrEP can take between 7 and 21 days to be completely effective. Afterward, you must continue to take PrEP every day for it to be effective.
- PrEP reaches maximum protection from HIV for receptive anal sex (bottoming) at about 7 days of daily use.
- For receptive vaginal sex and injection drug use, PrEP reaches maximum protection at about 21 days of daily use.
- No data are available for insertive anal sex (topping) or insertive vaginal sex.
If you can’t or don’t wish to commit to taking a pill every day, on-demand PrEP (also known as “2-1-1” or “event-driven” PrEP) may be right for you. Talk to a trusted physician to determine if this is the right fit.
Learn more about On-Demand PrEP:
Apretude, or cabotegravir, is the first long-acting injectable option for HIV prevention. The medication is initially given as two injections administered one month apart. Then, it is given as one injection every two months.
Learn more about injectable PrEP: